Home » Neutron Protein Crystallography: Hydrogen, Protons, and Hydration in Bio-Macromolecules by Nobuo Niimura
Neutron Protein Crystallography: Hydrogen, Protons, and Hydration in Bio-Macromolecules Nobuo Niimura

Neutron Protein Crystallography: Hydrogen, Protons, and Hydration in Bio-Macromolecules

Nobuo Niimura

Published April 10th 2011
ISBN : 9780199578863
Hardcover
233 pages
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 About the Book 

Neutron Protein Crystallography is one of the first books dedicated to the emerging field of neutron protein crystallography (NPC). The text covers all of the practical aspects of NPC, from the basic background of neutron scattering and diffraction,MoreNeutron Protein Crystallography is one of the first books dedicated to the emerging field of neutron protein crystallography (NPC). The text covers all of the practical aspects of NPC, from the basic background of neutron scattering and diffraction, to the technical details of neutron facilities, growth of high-quality crystals, and data analysis. The final chapter is devoted to providing many examples of using NPC to investigate a wide range of different proteins. It demonstrates how NPC can explore hydrogen bonds, protonation and deprotonation of amino acid residues, hydration structures, and hydrogen-to-deuterium exchange ratios.To avoid redundancy with other textbooks on X-ray protein crystallography (XPC), this book assumes a familiarity with the basics of XPC and strives to highlight and explain the differences between XPC and NPC. It is therefore especially useful for X-ray protein crystallographers who are eager to have a sound, scientific basis for judging if NPC is the right technique for furthering their experimental programs.